Wednesday 22 May 2013

The New Xbox One Live Features Add Advanced Social Gaming Features That Could Lead To True MMORPG Experiences

23While we don't have all of the details on the new Xbox Live features announced at today's Xbox One launch, it's clear that Microsoft is going all-in when it comes to social and multiplayer gaming. First, they are upping the number of dedicated servers for online play from 15,000 to 300,000 and nearly all of your content and game data will be store in the cloud.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/z5xbdtAZYoE/

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Readers Write: The dangers of immigration amnesty; Not all oil companies are alike

THE DANGERS OF IMMIGRATION AMNESTY

The April 8 cover story, "Amnesty: back to the future," understates the threat that a new amnesty for illegal immigrants poses to the United States. The 1987 amnesty was a massive failure on all counts: The border is still not secure, employers hire illegal immigrants without a credible deterrent, and the previous amnesty was subject to massive fraud.

If the government was unable to effectively monitor an amnesty of fewer than 3 million people then, what hope does it have to enforce an amnesty of a "known" 11 million or more now? Does the US have the resources or the will to investigate every immigrant's case for citizenship or application for asylum? If the risk is low and the benefit is high, common sense and past history suggest that people will lie.

Securing the border is a chimera and can never be the answer. The answer is to make interior America inhospitable to illegal immigrants. Birthright citizenship and chain migration also have to end. These policies haven't made sense in more than a century.

Michael G. Brautigam

Cincinnati

NOT ALL OIL COMPANIES ARE ALIKE

In her April 1 commentary, "Saving the Arctic's rich wildlife from an oil rush," Marilyn Heiman falls into the same trap as most critics of the oil industry who attribute disasters to human error or mechanical failure. While some accidents happen to any company, the truth of the matter is that certain oil companies have cultures of recklessness ? and it's that culture that causes disasters. These companies are arrogant, aggressive, and not easily restrained. I was a senior manager of an international oil company that was not arrogrant, so I know the difference.

The only way to prevent oil spill disasters ? especially a potential future spill in the Arctic ? is to deny drilling permits to those companies that display a disregard for safety and good practices or a reckless culture. It is easy enough to establish who those companies are. That might wake them up.

James Reed

Cathlamet, Wash.

Related stories

Read this story at csmonitor.com

Become a part of the Monitor community

Source: http://news.yahoo.com/readers-write-dangers-immigration-amnesty-not-oil-companies-141038066.html

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Tuesday 21 May 2013

Racial disparities in the surgical management of non-small cell lung cancer

Racial disparities in the surgical management of non-small cell lung cancer [ Back to EurekAlert! ] Public release date: 21-May-2013
[ | E-mail | Share Share ]

Contact: Nathaniel Dunford
ndunford@thoracic.org
American Thoracic Society

ATS 2013, PHILADELPHIA The surgical management of non-small cell lung cancer (NSCLC) in U.S. hospitals varies widely depending on the race of the patient, according to a new study.

"In most patients, the initial treatment for Stage I and Stage II NSCLC is surgery," said researcher Jayanth Adusumalli, MBBS, of the Creighton University Medical Center in Omaha, Nebraska. "In our study of more than 1,200,000 patients diagnosed with NSCLC in US hospitals between the years 2000 and 2010, we found statistically significant racial disparities in the surgical management of these patients."

The results of the study will be presented at the ATS 2013 International Conference.

The study included 1,200,955 patients from the National Cancer Data Base (NCDB); 975,229 of these patients had received their first course of treatment after initial diagnosis.

African-Americans were less likely to undergo surgery as initial treatment for Stage I and Stage II disease than Caucasians and Hispanics, and Hispanics were more likely to undergo surgery as initial treatment of Stage I and II disease than Caucasians." Overall, 82% of Caucasians, 79% of African Americans, and 76% of Hispanics received some form of treatment.

Among patients with Stage I disease, surgical intervention was performed in 78% of Caucasians, 73% of African Americans, and 82% of Hispanics. Corresponding figures for Stage II were 64%, 56% and 67%.

"The significant racial differences in the initial treatment of NSCLC that we found in our study may contribute to the recognized racial disparities in cancer patient outcomes," said Dr. Adusumalli. "Further research into the underlying causes of these treatment disparities may help improve the treatment and prognosis of all lung cancer patients."

###

* Please note that numbers in this release may differ slightly from those in the abstract. Many of these investigations are ongoing; the release represents the most up-to-date data available at press time.

Abstract 45364

Racial Disparities In Treatment Of Non Small Cell Lung Cancer In The US
Type: Late Breaking Abstract
Category: 02.03 - Disparities in Lung Disease and Treatment (BSHSR)
Authors: J. Adusumalli1, A. Singla1, A. Kallam1, P. Silberstein2; 1Creighton University Medical Center - Omaha, NE/US, 2Creighton
University School of Medicine - Omaha, NE/US

Abstract Body

Introduction: Surgery is the mainstay of treatment of loco regional of non-small cell lung cancer (NSCLC). This study compares the racial disparities in surgery as an initial treatment given to a NSCLC patient. Methods: We analyzed the National Cancer Data Base (NCDB) for differences in the first course treatment received for NSCLC amongst three different ethnic groups (Caucasian, African American and Hispanic). Chi square test was used for statistical analysis. Results: A total of 1,200,955 patients were diagnosed with NSCLC in US hospitals between 2000 and 2010 of which 975,229 patients were given the first course treatment. 82%, 79% and 76% of Caucasians, African Americans and Hispanics respectively received treatment (p


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Racial disparities in the surgical management of non-small cell lung cancer [ Back to EurekAlert! ] Public release date: 21-May-2013
[ | E-mail | Share Share ]

Contact: Nathaniel Dunford
ndunford@thoracic.org
American Thoracic Society

ATS 2013, PHILADELPHIA The surgical management of non-small cell lung cancer (NSCLC) in U.S. hospitals varies widely depending on the race of the patient, according to a new study.

"In most patients, the initial treatment for Stage I and Stage II NSCLC is surgery," said researcher Jayanth Adusumalli, MBBS, of the Creighton University Medical Center in Omaha, Nebraska. "In our study of more than 1,200,000 patients diagnosed with NSCLC in US hospitals between the years 2000 and 2010, we found statistically significant racial disparities in the surgical management of these patients."

The results of the study will be presented at the ATS 2013 International Conference.

The study included 1,200,955 patients from the National Cancer Data Base (NCDB); 975,229 of these patients had received their first course of treatment after initial diagnosis.

African-Americans were less likely to undergo surgery as initial treatment for Stage I and Stage II disease than Caucasians and Hispanics, and Hispanics were more likely to undergo surgery as initial treatment of Stage I and II disease than Caucasians." Overall, 82% of Caucasians, 79% of African Americans, and 76% of Hispanics received some form of treatment.

Among patients with Stage I disease, surgical intervention was performed in 78% of Caucasians, 73% of African Americans, and 82% of Hispanics. Corresponding figures for Stage II were 64%, 56% and 67%.

"The significant racial differences in the initial treatment of NSCLC that we found in our study may contribute to the recognized racial disparities in cancer patient outcomes," said Dr. Adusumalli. "Further research into the underlying causes of these treatment disparities may help improve the treatment and prognosis of all lung cancer patients."

###

* Please note that numbers in this release may differ slightly from those in the abstract. Many of these investigations are ongoing; the release represents the most up-to-date data available at press time.

Abstract 45364

Racial Disparities In Treatment Of Non Small Cell Lung Cancer In The US
Type: Late Breaking Abstract
Category: 02.03 - Disparities in Lung Disease and Treatment (BSHSR)
Authors: J. Adusumalli1, A. Singla1, A. Kallam1, P. Silberstein2; 1Creighton University Medical Center - Omaha, NE/US, 2Creighton
University School of Medicine - Omaha, NE/US

Abstract Body

Introduction: Surgery is the mainstay of treatment of loco regional of non-small cell lung cancer (NSCLC). This study compares the racial disparities in surgery as an initial treatment given to a NSCLC patient. Methods: We analyzed the National Cancer Data Base (NCDB) for differences in the first course treatment received for NSCLC amongst three different ethnic groups (Caucasian, African American and Hispanic). Chi square test was used for statistical analysis. Results: A total of 1,200,955 patients were diagnosed with NSCLC in US hospitals between 2000 and 2010 of which 975,229 patients were given the first course treatment. 82%, 79% and 76% of Caucasians, African Americans and Hispanics respectively received treatment (p


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-05/ats-rdi051313.php

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Saturday 18 May 2013

EA to ditch online passes | bit-gamer.net

EA to ditch online passes

The upcoming Battlefield 4 will not require an online pass to access multiplayer, unlike its predecessor.

EA is dropping online passes on its new titles following feedback from its players.

Talking to VentureBeat, EA senior director of corporate communications John Reseburg confirmed that no new titles from EA will feature an online pass requirement to access online functionality.

'Initially launched as an effort to package a full menu of online content and services, many players didn't respond to the format,' said Reseburg, speaking to VentureBeat. 'We've listened to the feedback and decided to do away with it moving forward.'

The player response cited is curious as at the time of the program's launch in 2010, EA reported that there was no 'significant pushback from the user' in a statement regarding the company's commitment to the program.

Reseburg was specifically talking about the upcoming Battlefield 4 and the online pass is not being discontinued on titles that already require them, only not implemented on future titles.

Games that currently use the online pass include Battlefield 3 and most of the entries in the EA Sports catalogue and there are no reported plans to phase these out at this time.

The move does not necessarily mean that EA is backing away from developing online features with Reseburg commenting that the company will still be committed to creating content and services that make players want to keep playing a title beyond its initial play through.

Judging by the success that EA often trumpets with regards to The Simpsons: Tapped Out, there's a possibility that this continued content creation could take the form of micro-transactions for its more traditional triple A titles, something that the company has experimented with before on Dead Space 3.

Online Pass
Online passes are an attempt to fight the second hand game market. As accessing online features requires this one-use activation code, if a second hand title is sold without an un-used code then a replacement can then be bought from the publisher directly, ensuring a revenue stream from used games. Other publishers including Activision and Ubisoft also use online passes.

Source: http://www.bit-tech.net/news/gaming/2013/05/17/ea-to-ditch-online-passes/1

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Obama?s OFA refusing to help on Keystone Pipeline (Americablog)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories Stories, RSS Feeds and Widgets via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/306516644?client_source=feed&format=rss

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Edward Furlong: Arrested Again After Fight With Girlfriend!

Source:

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Someone Finally Designed a Folding Chair That's Easy to Store

They're light, they're cheap, they're marginally comfortable, but ironically, folding chairs are rarely easy to stack and store. They're supposed to be, but their random curves and bulges make it a task that's frankly just not worth it?especially knowing that Folditure's ultra-flat hanging Tilt chairs are about to hit the market.

The hinges and supports on the Tilt that allow it to fold are designed so that when collapsed, the chair ends up being as flat as a pancake. So when stacked, the risk of avalanche is slim to nil. But stacking isn't your only option. The tilt also features an integrated hanger so a whole mess of them can be easily hung up like a closet full of clothes. There's no word on pricing or availability just yet, but Folditure has put crazier designs into production, so there's a good chance these will be too.

[Folditure via Chip Chick]

Source: http://gizmodo.com/someone-finally-designed-a-folding-chair-thats-easy-to-507608091

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Residents capture amazing videos in the face of tornadoes

A series of 16 violent tornadoes ransacked north Texas this week, killing six people and flattening entire neighborhoods. Seven people who were reported missing early Friday morning have now been accounted for, but the storms aren't over yet.

Severe thunderstorms were brewing in Alabama and Mississippi, and the Plains and the Midwest face threats of even more tornadoes this weekend, according the Weather Channel.

Some residents and daredevil storm chasers captured amazing footage as twisters plowed through Texas. We've rounded up some of the best videos.

A resident in Granbury, Texas took this video Wednesday as a tornado pounded the area just on the other side of Lake Granbury.

Tornado chaser Jason Cooley shot this footage Wednesday of a tornado that slammed into cities near Dallas. "We gotta go," says one woman in the video as the twister approaches. Later in the video, a man says, "We were just in a tornado."

One Texas resident captured a hail storm as it pounded DeCordova, Texas just before a major tornado hit Granbury, Texas on Wednesday.

Amy Castaneda created this Vine showing the size of the hail that pummeled Grandbury, Texas on Wednesday. The large hail damaged homes and injured residents. (Click image to view the Vine)

These images capture the destruction in the wake of the multiple tornadoes that tore through Texas.

Click here to follow Torrey on Twitter.

Source: http://news.yahoo.com/blogs/lookout/residents-capture-amazing-videos-face-tornadoes-005322352.html

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Star Trek Into Darkness Review: Small Time Fun

Making a Star Trek movie must be hard. A movie like Star Trek Into Darkness has to simultaneously treat its source material with acknowledgement, if not respect, and make itself feel new and original. There are a lot of ways to do that, but JJ Abrams seemed to choose, ?Just make it fun and figure the rest out.? He chose wisely.

Read more...

    


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/Fl5WESzd-fI/star-trek-into-darkness-review-the-fun-of-war-507643153

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Hot off the press: Seen and heard in Cannes

CANNES, France (AP) ? Associated Press journalists open their notebooks at the 2013 Cannes Film Festival:

___

JOHANSSON MOVING BEHIND THE CAMERA

Scarlett Johansson will make her directorial debut with an adaptation of Truman Capote's first novel, "Summer Crossing."

A publicist for the "Avengers" actress confirmed Thursday that Johansson will direct the long-lost book. "Summer Crossing" wasn't published until 2005, after the manuscript was recovered.

Financing for the film was assembled in Cannes. Capote's novel is about a 17-year-old debutant who, during a summer alone in 1945 New York, strikes up a romance with a Jewish valet parking attendant.

Johansson next appears in the independent film, "Don Juan," in which she co-stars with writer-director Joseph Gordon-Levitt.

? Jake Coyle, Twitter: http://twitter.com/jake_coyle

BRAFF NOT JUST DEPENDING ON KICKSTARTER

Zach Braff isn't just counting on the $2.7 million he raised on the crowd-funding platform Kickstarter to make his follow-up movie to "Garden State." Worldwide Entertainment has stepped in at Cannes as a financier for that film, "Wish I Was Here."

It's not uncommon for a film to find additional foreign investors at Cannes, but Braff has come under considerable criticism for relying on fans to bankroll his second directorial effort.

In one of the most high-profile Kickstarter campaigns, the "Scrubs" actor lobbied his fans to contribute money. The film's 38,000-plus backers earn various levels of rewards, from a copy of the script to a part in the film.

On his Kickstarter page, Braff denied that he was doing anything to undermine the spirit of crowd-funding. He said the additional funds would allow him to make the film as designed, within a budget of $5-6 million.

"I'm sorry for the hoopla," he wrote. "I'm sorry if your friends think you've been duped. But you haven't been. This is real. Crowd-sourcing films is here to stay."

Braff follows Rob Thomas' popular Kickstarter campaign to bring the cult TV show "Veronica Mars" back as a film. That project, too, had outside investment from Warner Bros.

? Jake Coyle, Twitter: http://twitter.com/jake_coyle

___

LUHRMANN: JAY-Z KEY TO 'GATSBY'

Not everyone is a fan of the hip-hop flavored soundtrack of "The Great Gatsby," but director Baz Luhrmann says using modern music was essential to capturing the spirit of F. Scott Fitzgerald's 1925 novel.

"We wanted the film to feel like how it would have felt to read the novel in 1925," the director told reporters at the Cannes Film Festival, where the movie provided opening-night screen fireworks and red-carpet glamor.

"Fitzgerald put music front and center in his novel. He took African-American street music called jazz and he put it right as a star in the book. People said, 'Why are you doing that? It's a fad, it'll be gone next week.' And he said, because I want this book to feel right here, right now."

Luckily for Luhrmann, "Gatsby" star Leonardo DiCaprio introduced him to Jay-Z, and the superstar agreed to help score the film. Two of Jay-Z's own tracks ? "$100 Bill" and the Grammy-winning jam "No Church in the Wild" ? feature on the soundtrack, and he elicited contributions from the wife Beyonce, Emeli Sande and Lana Del Rey.

Luhrmann also used the soundtrack to counter criticism of the absence of African-American speaking characters in the movie ? as in Fitzgerald's book.

"Jay said that music is a star in the film so I think there is a great African-American presence in this film and I am very, very grateful for it," he said.

?Jill Lawless, Twitter: http://Twitter.com/JillLawless

___

CANNES: WHAT ARE THE ODDS?

The French Riviera is a magnet for gamblers, so it's no surprise that odds makers are speculating furiously about who will win prizes from the Cannes Film Festival jury headed by Steven Spielberg.

Journalist and Cannes betting expert Neil Young ranks "Grisgris," by Chadian filmmaker Mahamat-Saleh Haroun, the early favorite for the Palme d'Or prize at 5-1. That is followed by "The Past," from Iran's Asghar Farhadi ? who won an Academy Award for "A Separation" ? at 11-2 and U.S. director James Gray's 1920s New York story "The Immigrant" at 13-2.

Other front runners are "Like Father, Like Son" from Korean director Kore-eda Hirokazu; Arnaud Desplechin's "Jimmy P," with Benicio del Toro as a traumatized Native American war veteran; and Alexander Payne's road movie "Nebraska."

But none of those films has even screened yet, and the odds are sure to change often before the prizes are handed out May 26.

?Jill Lawless, Twitter: http://Twitter.com/JillLawless

___

MOORE EXPRESSES ADMIRATION FOR JOLIE

Add Julianne Moore to those who are commending Angelina Jolie for her decision to reveal her choice to have a double mastectomy.

"I'm impressed with her and I'm impressed with her announcement, particularly because I feel there are so many women who are facing the same kind of choice, and it's a way to kind of validate and have solidarity with women who are having the same issue," Moore said in an interview from Cannes.

"It's obviously a really, really complicated (decision), and so I think her decision to go public about something like that can only help other women."

Jolie announced this week that she had both breasts removed recently because she had a very high chance of developing breast and ovarian cancer. Jolie has since had reconstructive surgery. Jolie's mother had breast cancer and died of ovarian cancer, while her grandmother suffered from ovarian cancer.

?Nekesa Mumbi Moody, Twitter: http://Twitter.com/nekesamumbi

___

CUISINE GETS A STARRING ROLE AT CANNES:

The chefs who prepared the dinner for the Cannes Film Festival's opening gala were as starry as the guests.

Anne Sophie Pic, who is a three-star Michelin chef, and Bruno Oger, who has two, collaborated for the four-course meal after the festival's opening night film of "The Great Gatsby" on Wednesday night.

Guests were treated to a menu that included King crab with shrimp and sea bass with rhubarb and celery. Select media were given a preview Tuesday.

Pic and Oger will join other chefs during the festival at the Electrolux Agora Pavillion to ensure that VIPs get top cuisine.

?Nekesa Mumbi Moody, Twitter: http://Twitter.com/nekesamumbi

Source: http://news.yahoo.com/hot-off-press-seen-heard-cannes-145337466.html

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U.S. regulator to vote on watered-down swap rules

By Douwe Miedema

WASHINGTON (Reuters) - Big banks are set to gain key concessions as the top U.S. derivatives regulator meets to vote on watered-down rules for swap trading that will chip away at Wall Street's dominance of the $630 trillion market.

The rules will allow banks to continue to negotiate deals over the phone, a practice critics say is hard to monitor, and lower the number of quotes investors need to get before entering a swap to move away from bilateral trading.

The Commodity Futures Trading Commission is writing a host of new rules based on lessons learned from the 2007-09 financial crisis, which highlighted the opacity of derivatives and triggered a regulatory crackdown.

On Thursday, the CFTC's five members - three Democrats and two Republicans - are expected to vote in a public meeting starting at 10 a.m. (1500 GMT) on new platforms for swaps that will bring bilateral trading to an end.

Bilateral trading, which is also seen as difficult to monitor, was blamed for exacerbating the crisis.

"We will bring to this once-opaque marketplace the transparency that Congress and President Obama laid out," CFTC Chairman Gary Gensler said on a call with journalists when presenting the rules on Wednesday.

The swaps market had modest beginnings in the 1980s, offering companies risk management tools, but rapidly started to attract speculators, causing it to mushroom out of regulators' sight in the following decades.

(Graphic with key metrics of the swaps market: http://link.reuters.com/beh28t)

In an important nod to an industry dominated by big banks such as Citigroup Inc, Bank of America Corp and JPMorgan Chase & Co, the CFTC will continue to allow swaps deals to be negotiated over the telephone.

Derivative brokers such as ICAP Plc, GFI Group Inc and Tullett Prebon Plc, which sign up for the bulk of trading between banks, had lobbied hard to retain so-called voice-broking, the core of their business.

The rules for the new platforms, called Swap Execution Facilities (SEF), were one of the last remaining building blocks in the CFTC's rules, which are part of the Dodd-Frank overhaul of the financial industry after the crisis.

Another compromise in the rules for SEFs was the minimum number of quotes that a prospective client needs to get before entering a swap deal, a requirement aimed at bringing more transparency to the market.

The rules set a minimum of three quotes in so-called request-for-quote trading systems after a one-year phase-in period when the minimum number of quotes is two. The CFTC had initially proposed a minimum of five quotes.

Critics of the industry had said the lower the number, the smaller the move away from bilateral trading.

(Reporting by Douwe Miedema; Editing by Lisa Von Ahn)

Source: http://news.yahoo.com/u-regulator-vote-watered-down-swap-rules-133320305.html

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Pelosi: GOP using IRS, Benghazi and DOJ issues as ?evasion? tactic

House Minority Leader Nancy Pelosi (Mark Wilson/Getty Images)

House Minority Leader Nancy Pelosi accused Republicans of using the alleged scandals involving the Internal Revenue Service, Department of Justice and the State Department as an "evasion" from passing bills she said would increase job growth.

Over the past few weeks, the IRS admitted to targeting conservative groups applying for nonprofit status and the Department of Justice seized AP journalists' phone records. Earlier this week, the White House provided more details about the Obama administration's initial response to last year's attack on an American compound in Benghazi, Libya.

Speaking to reporters on Thursday, Pelosi called the IRS and DOJ issues "legitimate"?she condemned the IRS' practices outright?but suggested that Republicans were trying to exploit them for political gain.

"Any issue that comes up, they will try to exploit," Pelosi said. "And some of them are legitimate issues, but they should not dominate everything. And so, what I think is that they have used talking points on Benghazi, they will use the IRS, they will use the AP, they will use these as subterfuges, evasions, of what the American people want us to do here. They want us to create jobs.

"Now, if you're a party in Congress and you have no intention of creating jobs, you want to change the subject," she continued. "So I think this is as much about forcing their anti-government ideology of not a public role in the creation of jobs as well as undermine the president of the United States."

Source: http://news.yahoo.com/blogs/ticket/pelosi-gop-using-irs-benghazi-doj-issues-evasion-173845377.html

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Thursday 16 May 2013

Stem cells recovered from cloned human embryos

This undated image made available by the Oregon Health & Science University in May 2013 shows developing cloned human embryos. Scientists have finally recovered stem cells from cloned human embryos, a longstanding goal that could lead to new treatments for such illnesses as Parkinson's disease and diabetes. In the Wednesday, May 15, 2013 edition of the journal Cell, scientists at the Oregon Health & Science University report harvesting stem cells from six embryos. Shoukhrat Mitalipov, who led the research, said the success came not from a single technical innovation, but from revising a series of steps in the process. (AP Photo/Oregon Health & Science University)

This undated image made available by the Oregon Health & Science University in May 2013 shows developing cloned human embryos. Scientists have finally recovered stem cells from cloned human embryos, a longstanding goal that could lead to new treatments for such illnesses as Parkinson's disease and diabetes. In the Wednesday, May 15, 2013 edition of the journal Cell, scientists at the Oregon Health & Science University report harvesting stem cells from six embryos. Shoukhrat Mitalipov, who led the research, said the success came not from a single technical innovation, but from revising a series of steps in the process. (AP Photo/Oregon Health & Science University)

This undated image made available by the Oregon Health & Science University in May 2013 shows a stem cell colony developed from cloned human embryos. Scientists have finally recovered stem cells from cloned human embryos, a longstanding goal that could lead to new treatments for such illnesses as Parkinson's disease and diabetes. In the Wednesday, May 15, 2013 edition of the journal Cell, scientists at the Oregon Health & Science University report harvesting stem cells from six embryos. Shoukhrat Mitalipov, who led the research, said the success came not from a single technical innovation, but from revising a series of steps in the process. (AP Photo/Oregon Health & Science University)

(AP) ? Scientists have finally recovered stem cells from cloned human embryos, a longstanding goal that could lead to new treatments for such illnesses as Parkinson's disease and diabetes.

A prominent expert called the work a landmark, but noted that a different, simpler technique now under development may prove more useful.

Stem cells can turn into any cell of the body, so scientists are interested in using them to create tissue for treating disease. Transplanting brain tissue might treat Parkinson's disorder, for example, and pancreatic tissue might be used for diabetes.

But transplants run the risk of rejection, so more than a decade ago, researchers proposed a way around that: Create tissue from stem cells that bear the patient's own DNA, obtained with a process called therapeutic cloning.

If DNA from a patient is put into a human egg, which is then grown into an early embryo, the stem cells from that embryo would provide a virtual genetic match. So in theory, tissues created from them would not be rejected by the patient.

That idea was met with some ethical objections because harvesting the stem cells involved destroying human embryos.

Scientists have tried to get stem cells from cloned human embryos for about a decade, but they've failed. Generally, that's because the embryos stopped developing before producing the cells. In 2004, a South Korean scientist claimed to have gotten stem cells from cloned human embryos, but that turned out to be a fraud.

In Wednesday's edition of the journal Cell, however, scientists in Oregon report harvesting stem cells from six embryos created from donated eggs. Two embryos had been given DNA from skin cells of a child with a genetic disorder, and the others had DNA from fetal skin cells.

Shoukhrat Mitalipov of the Oregon Health & Science University, who led the research, said the success came not from a single technical innovation, but from revising a series of steps in the process. He noted it had taken six years to reach the goal after doing it with monkey embryos.

Mitalipov also said that based on monkey work, he believes human embryos made with the technique could not develop into cloned babies, and he has no interest in trying to do that. Scientists have cloned more than a dozen kinds of mammals, starting with Dolly the sheep.

The new work was financed by the university and the Leducq Foundation in Paris.

Dr. George Daley, a stem cell expert at Children's Hospital Boston who didn't participate in the work, called the new results "one landmark step in a very long journey" toward creating DNA-matched transplant tissue.

Now, Daley said, scientists must compare the embryo-cloning approach with another technology that reprograms blood or skin cells directly into substitutes for embryonic stem cells. This reprogramming approach is technically simpler and doesn't involve embryos or require the donation of human eggs, and it was widely acclaimed when it was reported in 2007. Its Japanese developer shared a Nobel Prize last year.

But these substitute cells show some molecular differences compared to embryonic ones, which has led to questions about whether they can safely be used for treating patients. So it's essential to compare the cells from the two methods, Daley said.

The new results mean "we have another tool," he said. "We have to learn more about this tool."

Daley said he believed scientists will prefer using the reprogramming approach unless it can be proven "beyond a shadow of a doubt" that embryo cloning produces better cells for treating patients.

Mitalipov said he believed his technique would present a particular advantage for treating patients with a certain type of rare diseases. These are caused by mutations in genes of the mitochondria, the power plants of cells. He noted his technique, unlike the cell-reprogramming approach, would supply tissue with new mitochondrial genes that could replace defective ones. Those new genes would come from the egg.

The Rev. Tad Pacholczyk, director of education for National Catholic Bioethics Center, an independent think tank in Philadelphia, reiterated his opposition to embryo cloning, calling the approach unethical.

"It involves the decision to utilize early human beings as repositories for obtaining desired cells," he said. "You're creating them only to destroy them."

Marcy Darnovsky, executive director of the Center for Genetics and Society in Berkeley, Calif., said she was glad that Mitalipov doubted the embryos could be used to clone babies. She said the report still provides a good opportunity for the federal government to ban the use of cloning for reproduction.

___

Online:

Journal Cell: http://www.cell.com/

___ Malcolm Ritter can be followed at http://www.twitter.com/malcolmritter

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/b2f0ca3a594644ee9e50a8ec4ce2d6de/Article_2013-05-15-Stem%20Cells/id-15fa26f4c79a497a8a32b843755706de

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The wait for mobile app voice control is finally over for DirecTV customers?or those with iPhones, a

The wait for mobile app voice control is finally over for DirecTV customers?or those with iPhones, at least. Presumably, an Android version should be soon to follow.

Read more...

    


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/EGSvmYefQE4/the-wait-for-mobile-app-voice-control-is-finally-over-f-506669593

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Hitzfeld tips Bayern for European glory | bettor.com

The former manager has admitted that Bayern Munich are stronger than Borussia Dortmund and is looking forward to a great encounter

Ottmar Hitzfeld feels that it is great for German football that Bayern Munich and Borussia Dortmund have reached the final of the UEFA Champions League this season. Bayern downed Barcelona in the semi-final whereas Dortmund got rid of Real Madrid at the same stage.

The former Bayern and Dortmund manager claimed that the Bavarians have a slight edge over their rivals as they have great quality in their squad and have had an exquisite season as well. He is expecting a mouth-watering encounter and is confident that the fans will not be disappointed with the game.

?This is a dream for German football that there is this final. And then, for me, also with Dortmund and Bayern being my former clubs. I believe that Bavaria are the slight favourites, but both meet at eye level,? he was quoted as saying in an interview.

The former tactician added that it is exceptional for Dortmund to reach the final as nobody had expected them to beat the likes of Malaga CF and Real Madrid.

?Dortmund reaching the final is sensational [but at Bayern] the situation is different. One team craves the Champions League and after losing two finals, one team just wants to go win the match,? he continued.

On the other hand, the current Swiss national team manager added that Pep Guardiola will have a great squad at his disposal when he joins the team at the end of the season. He added that the former Barcelona manager ticks all the boxes and will be a great success at the Bavarian club.

?He can look forward to taking over an intact, world-class team that he can continue to develop and can bring many titles,? he concluded.

Bayern Munich and Borussia Dortmund will face each other on May 25 at the Wembley Stadium in London. The Reds have reached their third Champions League final in four years and have lost on the previous two occasions to the likes of Inter Milan and Chelsea.

Source: http://blogs.bettor.com/Hitzfeld-tips-Bayern-for-European-glory-a215353

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House farm bill moves ahead with big cut in food stamps

By Charles Abbott

WASHINGTON (Reuters) - A Republican-controlled panel in the U.S. House of Representatives on Wednesday approved the biggest cuts in food stamps for the poor in a generation and a potentially expensive expansion of federally subsidized crop insurance.

The House Agriculture Committee approved a five-year, $500 billion farm bill on a 36-10 vote. The next step will be debate by the full House, which is likely to start in June.

Congress is months late in writing a new farm law. The Senate Agriculture Committee advanced its version on Tuesday and the full Senate is set to begin debate on Thursday.

The House and Senate bills each end the $5 billion-a-year direct-payment subsidy, long a target of reformers, and spin off at least three new types of crop insurance.

Almost half the savings in the House bill would come from a $20.5 billion cut over 10 years in spending on food stamps for low-income Americans.

The House plan would restrict eligibility and require closer accounting of certain costs. It would be the largest cut in food stamps since the 1996 welfare reform law, experts say.

Food stamps are seen as the make-or-break issue for the latest farm bill, rather than crop subsidies, which have traditionally been the focus of debate.

An urban-rural partnership traditionally carries farm bills to passage - city lawmakers back generous farm subsidies in exchange for well-funded nutrition programs - but threatens to shatter this time around.

The farm bill died last year amid Democratic opposition to Republican demands for $16 billion in food stamp cuts. The bill was never debated by the full House.

A STEP TOO FAR?

"This goes too far," Democrat Jim McGovern said of the latest bill. The Massachusetts lawmaker lost 27-17 on a mostly party-line vote when he tried to eliminate the food stamp cuts in the new bill.

Iowa Republican Steve King said high food stamp enrollment would "expand the dependency class" and Austin Scott, a Georgia Republican, suggested it was unfair that "nutrition is getting five times as much as production agriculture" in the bill.

About 2 million people, or 4 percent of participants, would lose food stamps under language in the new House bill to eliminate so-called categorical eligibility, created by welfare reform, according to the Center for Budget and Policy Priorities, a non-partisan think tank.

Some 45.6 million people, many of them impoverished elderly or working-poor families with children, received food stamps at latest count.

While the bill expands crop insurance spending by $9 billion over a decade, it would cut traditional subsidies by $22 billion, according to the Congressional Budget Office. Aides to Agriculture Committee Chairman Frank Lucas said the farm safety net would shrink overall.

Federal payments could surge above current levels if commodity prices fall sharply, said agricultural economist Vince Smith of Montana State University. When crop insurance and crop supports are considered together, "the government is responsible for a much larger share of any farm income shortfall," Smith said.

Cotton growers would get a special revenue insurance program to replace subsidies that the World Trade Organization says violated trade rules. The government would pay 80 percent of the premium. Peanuts would get a separate revenue insurance program.

"Companies underwriting federal crop insurance are likely to be among the major beneficiaries of the new farm bill when it becomes law," said analyst Mark McMinimy of Guggenheim Washington Research Group.

U.S. commodity prices are at historically high levels so farm program changes may not be felt immediately for most crops. However, the Senate and House farm bills set peanut supports slightly above the projected market price and raise the "target" price for rice by 27 percent to 33 percent.

Both versions of the bill would make slightly more land available for growing crops by shrinking the Conservation Reserve, a program that pays farmers to idle fragile land for 10 years or more. The House would cap the reserve at 24 million acres and the Senate at 25 million acres, down from the 27 million acres now idled.

(This story corrects the attribution to Smith from Lucas in the 15th paragraph)

(Reporting By Charles Abbott; Editing by Ros Krasny and Jim Loney)

Source: http://news.yahoo.com/us-house-farm-bill-moves-ahead-big-cuts-040457897.html

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California Supreme Court Upholds Local Government Bans on Pot ...

In its most important land use decision since 2011, the California Supreme Court has upheld local governments? power to ban marijuana dispensaries within IEtheir jurisdictions. Last week the court unanimously rejected marijuana advocates? claim that such local bans are preempted by California state law. The Supreme Court?s opinion in City of Riverside v. Inland Empire Patients Health and Wellness Center, Inc. can be found here.

The seeds of this dispute can be found in California?s Compassionate Use Act, enacted by state voters as an initiative measure in 1996. Promoted by its sponsors as a narrow exception to California?s criminal laws generally prohibiting pot use, the initiative decriminalizes marijuana use for purely medicinal purposes under a doctor?s care. The problem is that the measure was poorly drafted, and over the years pot dispensaries proliferated throughout California, with advertising and marketing efforts targeted mostly at recreational pot users. That, in turn, created a political backlash in California, and numerous land use conflicts with neighboring schools, churches and residents.

In recent years, a growing number of California cities and counties gave up trying to resolve those conflicts, choosing instead to simply prohibit pot dispensaries within their local borders. (Some 193 California cities and 20 counties have instituted such bans.) Numerous commercial dispensaries and marijuana advocates went to court, challenging the local bans as preempted by the 1996 initiative and follow-up 2003 legislation. In other cases?including the one just decided by the California Supreme Court?local governments filed public nuisance actions against dispensary owners who refused to comply with the municipal bans on pot dispensaries.? In both instances, the marijuana shops took the position that the local bans were preempted by the 1996 initiative and related state laws.

The California Supreme Court has now rejected that preemption challenge. Writing for the court in Inland Empire, Justice Marvin Baxter declared that California state laws ?remove state level criminal and civil [penalties] from specified medical marijuana activities but they do not establish a comprehensive state system of legalized medical marijuana, or grant a right of convenient access to marijuana for medicinal use?or mandate local accommodation of medical cooperatives, collectives or dispensaries.?

The Inland Empire decision resolves a dispute among California?s six intermediate Courts of Appeal.? All six had previously opined on the preemption question, reaching inconsistent results.

What the Supreme Court?s decision does not resolve is a separate, related and even more important preemption issue: whether California?s Compassionate Use Act is itself preempted by federal law.? The use and possession of marijuana is a criminal offense under the federal Controlled Substances Act, which makes no exception for medicinal use of marijuana.? Thus, many law enforcement officials and marijuana opponents have argued that California?s Compassionate Use Act is preempted by contrary federal law.? (The California Supreme Court actually had a case on its docket raising this latter issue, but it was dismissed before the justices could decide the issue on the merits.)

In 2011, California?s four U.S. Attorneys launched a coordinated effort to prosecute pot offenses under federal criminal law in this state.? (So far, federal prosecutors have focused their criminal enforcement efforts on large-scale marijuana growers and marketers, rather than individual users.)? California was the first state to decriminalize marijuana use under a doctor?s care, in 1996.? Since then, however, a number of other states including Colorado and Washington have? gone further, legalizing marijuana use even for recreational purposes.? It will be interesting to see if federal prosecutors respond to this latter development by re-focusing their criminal enforcement efforts on those jurisdictions that now reflect a more relaxed view of marijuana use than does California.

Meanwhile, the California Supreme Court?s decision in Inland Empire represents a major victory for California local governments that exercise their land use authority to proscribe private activities government leaders deem a threat to public health and safety.? In recent years the California Legislature has circumscribed local land use authority in several areas?e.g., by abolishing California redevelopment agencies and through state efforts to mitigate greenhouse gas emissions.? But Inland Empire demonstrates that California cities and counties still retain substantial land use authority, at least when local land use regulations are not in direct conflict with state law.

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Source: http://legalplanet.wordpress.com/2013/05/14/california-supreme-court-upholds-local-government-bans-on-pot-dispensaries/

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Private Sales Club Privalia Tops Up Its Total Funding To $251M, With $32M From New Investor Sofina, To Drive Latam Growth

PrivaliaAnother funding raise for a collaborative consumption startup: Spain-based private sales club Privalia, which sells branded clothes and accessories at discounted prices to members in the five markets it currently plays in, has closed a new ?25m round ($32.3m). The company did not specify which round this latest raise falls under but has previously raised a total of $218m in two rounds.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/T8dsVof5aLw/

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Franz Kafka Heroes Challenge Traffic Tickets - Courthouse News ...

Franz Kafka Heroes Challenge Traffic Tickets

?????BIRMINGHAM, Ala. (CN) - A class action claims the City of Center Point and Redflex Traffic Systems illegally ticket drivers by threatening them with a court appearance if they refuse to pay fines, though "no such court exists."
?????Redflex owns and operates the traffic cameras for Center Point, which photographs cars believed to run red lights or stop signs or speed.
?????Such traffic-enforcement systems have been challenged, usually unsuccessfully, in courts all over the country.
?????This one is a bit odd, though. It claims that the law that made the traffic cameras legal also gave ticketed drivers the right to appeal - but there are no courts authorized to hear the appeals, the two named plaintiffs say.
?????Rhonda Lashon Stubbs and Celeita Snow sued the city and Redflex in Jefferson County Court.
?????Stubbs's Lexus, license plate IMNGOD, was ticketed twice, allegedly for running the same stop sign on different days. Snow's Mercedes Benz was issued 14 citations.
?????Snow says she repeatedly requested hearings on her tickets, and the city granted them, then "postponed" them, but never set a new date.
?????It can't, she says, because there is no court that can hear it.
?????"Ms. Stubbs paid the Notice of Violation because the Defendants left her with the false impression that the administrative hearing would be binding and would be conducted by the 'Municipal Court,'" the complaint states. "Currently, however, the Defendants strenuously argue that no such court exists. By leaving the Plaintiff with the false impression that she would appear in front of a 'court,' the Notice of Violation carried the full imprimatur of the State of Alabama and misled and intimidated Ms. Stubbs and the Class members into paying the 'fine.'
?????"Similarly, the Notice of Violation sent to Stubbs and other members of the Class did not explain that the $100 'fine' could not be collected unless the City filed a later, separate civil suit. Neither Ms. Stubbs nor any other Class member was informed that the Notice of Violation was not judicial in nature but was actually a non-binding collection notice."
?????In fact, the plaintiffs say, a state judge has told the city that its system is illegal.
?????The complaint states: "On August 17, 2012, an order was entered by Jefferson County Circuit Court Judge David N. Lichtenstein in City of Center Point v. Kenneth Crowder, CV-2012-0929 whereby this Court found that the Alabama District Courts do not have jurisdiction to hear appeals of any matters concerning fines, adjudications, or other action pursuant to Ordinance 2011-02. Therefore, the 'appeal' rights granted in the statute are defective as contrary to the Alabama Constitution.
?????"As a result of deficiencies in the Statute and Ordinance - as pointed out by Judge Lichtenstein - no meaningful appeal lies from any decision of the hearing officer appointed by the Mayor. Act 2011-580 grants rights of appeal and the Due Process Clause requires the opportunity for meaningful review; absent that, the Statute and the Ordinance are unconstitutional as applied and are due to be stricken."
?????Every member of the class, in other words, becomes a hero, or victim, of his or her own Kafka novel.
?????The plaintiffs seek declaratory judgment, costs, and damages for civil rights violations, suppression of material facts, and unlawful debt collection practices.
?????Their lead counsel is Samuel M. Hill.
?????Franz Kafka (1883-1924) wrote novels and stories in which the hero, often named Josef K., is summoned to appear at a court he cannot reach, for a crime uncertain.
?????Center Point, pop. 23,000, is a suburb of Birmingham.?

Source: http://www.courthousenews.com/2013/05/14/57607.htm

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American begins 15 years of hard labor in North Korean 'special prison'

Yonhap via Reuters

Kenneth Bae, 44, was convicted of "hostile acts" against North Korea.

By Alastair Jamieson, Staff writer, NBC News

An American tour operator sentenced to 15 years of hard labor in North Korea?has begun his sentence at a ?special prison,? state media reported Wednesday.

Kenneth Bae,?44, stood trial last month accused of ?hostile acts? against the repressive regime.

Bae, who is from Washington state, was convicted of an attempt to topple the government through ?state subversion? according to a brief report on the Korean Central News Agency's website.

?Pae Jun Ho, an American citizen, started his life at a special prison on Tuesday,? the report said, referring to him by his Korean name.

He is one of at least three other U.S. citizens who are also devout Christians to have been detained by North Korea in recent years.

While North Korea's constitution guarantees freedom of religion, in practice only sanctioned services are tolerated.

Washington state Rep. Cindy Ryu?told The Herald newspaper?in December that Bae might have been doing missionary work in North Korea.

"Many of us are third- and fourth-generation Christians and many of our pastors are originally from North Korea," Ryu said. "We want to visit our home country, but in North Korea you cannot say you are a missionary."

A?Facebook page?has been set up titled ?Remember Ken Bae, Detained in North Korea.?

The Supreme Court of North Korea sentenced American Kenneth Bae to 15 years of hard labor for "crimes against the country." Bae arrived with a tourist group on Nov. 3 and has been held ever since.

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Tuesday 14 May 2013

Sony Xperia ZR announced, allows underwater photography down to five feet of depth (video)

Sony's ratcheted up its water-resistant device tech a notch with the launch of the Xperia ZR, a new 4.6-inch, 720p Android smartphone that's waterproof to 1.5 meters (5 feet). Sony boasts that its new device will let you film your snorkeling adventures in full HD quality, with HDR in both video or 13-megapixel stills thanks to the Exmor RS image sensor -- there's also a dedicated camera button like the one on the Xperia ZL. The handset packs a Snapdragon S4 Pro quad-core 1.5GH CPU, 2GB RAM, LTE, NFC, Sony's Walkman album and movie apps and a notable OptiContrast OLED screen with Bravia tech to reduce glare "even in bright sunlight." There's no word yet on pricing or availability, but as soon as we hear more, we'll try to prep you ahead of that next beach-bound holiday. Meanwhile, you can check the galleries, PR and video after the break for more.

Update: As Xperia Blog found out, the Xperia ZR is actually the international version of Japan's upcoming Xperia A SO-04E -- the one we saw popping up in the FCC database.

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Source: http://www.engadget.com/2013/05/13/sony-xperia-zr-launched-waterproof/?utm_medium=feed&utm_source=Feed_Classic&utm_campaign=Engadget

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Survey: Americans love Adele, not Bieber

Getty Images file

By Randee Dawn, TODAY contributor

Americans may buy Justin Bieber's music, but that doesn't mean they like him much.?According to a recent survey from Public Policy Polling, the pop idol is just not considered very likable: He received 54 percent unfavorable ratings and only 20 percent likable ones in the poll, which surveyed 571 voters on May 6 and 7 across the U.S.?

PPP was testing the favorability ratings of some of today's biggest music stars, and -- perhaps unsurprisingly -- a Brit earned the most accolades: Adele had 54 percent likability; close on her heels were Taylor Swift (53 percent), Justin Timberlake (52 percent) and Beyonce (51 percent). But breaking that 50 percent mark was hard for virtually everyone else -- including Jay-Z (25 percent), Lady Gaga (29 percent) and Rihanna (30 percent).?

No surprise: Chris Brown's likability rating? A mere 13 percent. (And only 8 percent said that Rihanna should get back together with Brown; 67 percent say forget about that relationship.)

Bieber's numbers were the only ones that ran across party lines -- Democrats, Republicans and Independents all said they had negative views of him. Meanwhile, given the choices of Adele, Bieber, Beyonce, Brown, Jay-Z, Timberlake, Lady Gaga or Rihanna, as President of the U.S.,?34 percent chose Timberlake.?

That said, when asked if Timberlake should keep making music, acting, reuniting with N'Sync or playing golf, the biggest group said stick with the songs (40 percent).

PPP surveyed 571 voters nationwide on May 6th and 7th. The margin of error is +/-4.1%. This poll was not paid for or authorized by any campaign or political organization. PPP surveys are conducted through automated telephone interviews.

Source: http://entertainment.nbcnews.com/_news/2013/05/14/18247849-survey-confirms-a-hunch-americans-love-adele-dont-like-justin-bieber?lite

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